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Why Choose Our Pain Creams

Topical creams give prescribers the opportunity to treat their patients at the site of pain by providing high drug concentrations that result in a greater analgesic effect by eliminating possible side effects associated with traditional oral and injectable medications.

  • Superior therapeutic outcomes through locally enhanced topical delivery
  • Improved patient compliance
  • Fewer overall side effects than typically found with oral medication
  • Reduced risk of dependency/abuse
  • Concentration of therapeutic levels of medication in tissues while maintaining low serum concentration
  • Reduced systemic toxicity
  • Avoidance of first-pass metabolism and GI upsets
  • Decreased risk of drug-to-drug interactions

World Class Compounding

Compounding is what we call the “art” of pharmacy, providing solutions to address the specific and unique needs of individual patients. This practice dates back to the origin of pharmacy. Before mass production of medications by manufacturing companies became the norm, compounding medications was a part of the daily life of a pharmacist.  Pharmacists compounded almost all prescriptions until the mid-twentieth century when most dispensed drugs began coming directly from large pharmaceutical companies.  Today pharmaceutical compounding is growing in popularity as physicians search for treatment alternatives for their patients who do not respond well to the typical “one size fits all” therapies.

Our team of licensed pharmacists combine this “art” with the latest medical knowledge and state of the art equipment to completely customize FDA approved ingredients into specialized pharmaceutical compounds. These pharmaceutical solutions can greatly enhance patient care in individuals who are not receiving adequate treatment with the commercially manufactured options.

Our team of dedicated professionals is focused on delivering the most effective compounds possible to meet patients’ and healthcare professionals’ needs.

Joint Pain Cream

Joint pain is described as any discomfort arising from any joint. The pain is often referred to as arthritis or arthralgia. Joint pain can range from mild discomfort to debilitating pain causing severe limitations in mobility. Although mostly prevalent in the older population, anyone can be affected by joint pain. Daily pain can affect mobility, independence, and quality of life.

NSAIDs have long been known to be highly effective at treating joint pain; however, their risky side effects include gastrointestinal discomfort, gastrointestinal bleeding, and cardiovascular events. Many patients are unable to take oral NSAIDs due to these side effects, but when applied topically, NSAID therapy is a viable and beneficial way to treat joint pain for these patients. Topical pain creams used for joint pain not only drastically reduce these side effects, but also allows for long term use. As a part of the multi-modal treatment plan, topical pain creams can improve a patients’ mobility, independence and quality of life.

National Pain Custom Pharmacy can provide a joint pain cream customizable to a patient’s needs.

Ketoprofen – is a potent non-steroidal anti-inflammatory agent (NSAID) with augmented absorption whose use is best indicated for pain involving torn muscles and like injuries. 

Flurbiprofen – is a potent non-steroidal anti-inflammatory agent (NSAID).

Ketamine – NMDA receptor antagonist used as a pain blocker.

Lidocaine – is a local anesthetic.

Bupivacaine – local anesthetic that works by acting as a sodium channel blocker, preventinc ectopic neuropathic impulses.


Joint Pain Symptoms

  • Pain
  • Stiffness
  • Swelling
  • Warmth at Joint
  • Weakness
  • Fatigue

Musculoskeletal Pain Cream

Musculoskeletal pain is pain that affects the muscles, ligaments, tendons, and bones. This type of pain can commonly be found in the back, neck, and shoulder. Many patients suffer from widespread musculoskeletal pain.

National Pain Custom Pharmacy can provide a topical musculoskeletal pain cream that will target the specific site of pain. The cream contains multiple agents that target the various pathways that cause musculoskeletal pain. Using a topical cream can decrease the amount of oral pain medications needed, reduce gastrointestinal distress, and decrease the potential for side effects. Furthermore topical cream for musculoskeletal pain is much less invasive and is considered by many to be safer than traditional medications or surgical procedures.

Ketoprofen – is a potent non-steroidal anti-inflammatory agent (NSAID) with augmented absorption whose use is best indicated for pain involving torn muscles and like injuries.

Flurbiprofen – is a potent non-steroidal anti-inflammatory agent (NSAID).

Cyclobenzaprine – is a muscle relaxant. Possesses anti-neuropathic properties by inhibiting sodium channels as it is structurally related to the tricyclic antidepressants.

Baclofen – an antispasmodic agent used topically for its pain relieving properties. It is a GABA receptor agonist which reduces pain, especially in combination with NSAIDs.

Lidocaine – is a local anesthetic.


Common Musculoskeletal Pain Conditions

  • Back Pain
  • Neck Pain
  • Tendonitis
  • Myalgia
  • Stress Fractures

Neuropathic Pain Cream

Neuropathic pain can have many causes. Symptoms may include burning, tingling, numbness, and shocks of electricity. These symptoms can drastically affect a person’s quality of life. Treating nerve pain can sometimes be difficult. Oral medications, although effective, have many undesirable side effects. Topical creams for nerve pain can drastically reduce those negative effects by providing relief to the nerves located at the site of the pain while keeping systemic absorption to a minimum. Delivering the right medication to the appropriate trigger point can decrease the amount of oral medication the patient uses.

National Pain Custom Pharmacy can combine the right medications into a topically applied cream that will treat the specific triggers that cause neuropathic pain. Our various pain creams can be customized to meet an individual patient’s needs.

Ketamine – acts as an NMDA antagonist and is used as an anesthetic.

Gabapentin – a glutamate antagonist, has been used for widespread neuropathy.

Baclofenan antispasmodic agent used topically for its pain relieving properties. It is a GABA receptor agonist which reduces pain, especially in combination with NSAIDs.

Amitriptyline – interferes with the way the nerve impulses are transmitted, reducing pain sensation.

Lidocaine – is a local anesthetic.


Common Types of Neuropathic Pain

  • Fibromyalgia
  • Sciatica
  • Diabetic Neuropathy
  • Chemo-Induced Neuropathy
  • Shingles
  • HIV-induced Neuropathy
  • Neuropathy from Injury

Vascular Pain Cream

Vascular pain usually occurs in the peripheral extremities. Signs and symptoms include leg pain when walking, burning, cramping, numbness, or weakness. Vascular pain is caused by fatty build up in the arteries which causes the smooth muscle on the interior walls of the arteries to “stiffen” or harden.

Oral medications, procedures and exercise have all shown some benefit in relieving vascular pain, but are not always an option for every patient who suffers from vascular pain. A topical cream allows these patients an alternative to traditional treatments. Compounding specific ingredients that work together to target the pain at the actual site of the pain can provide patients relief they couldn’t find with current treatment options.

Although vascular pain is difficult to treat, we believe that a topical cream from National Pain Custom Pharmacy can be a beneficial adjunct to your patient’s therapy.

Nifedipine – works locally in the tissues to dilate capilaries and relax smooth muscle.

Clonidine – provides analgesic effects and potentiates the effects of other anesthetics in the formula.

Amitriptyline – is a tricyclic antidepressant and when used topically for pain relief has been shown to reduce nerve pain. It can also improve the effects of other analgesic agents.

Gabapentin – helps to reduce any underlying neuropathic pain that commonly accompanies vascular pain.

Migraine Transdermal Gel

Migraine symptoms include severe pain in one or both sides of the head, dizziness, nausea, vomiting, visual disturbances, and sensitivity to light and sound. Most of the therapeutic agents recommended to treat migraine attacks are given orally. Oral route administration has disadvantages including first pass metabolism, liver toxicity, etc. Furthermore, oral drugs often cause additional gastrointestinal distress to an already suffering patient.

Transdermal delivery systems for migraine treatment are desirable for many patients, especially those who experience gastrointestinal discomforts. The pharmacists at National Pain Custom Pharmacy can compound specific topical gels to deliver the drugs to the site of the headache.

Sumatriptan – a 5-hydroxytryptamine 1D (5-HT 1D) receptor antagonist and the first of the triptan family of drugs to be used in treating migraine. Sumatriptan appears to act selectively on the blood vessels located within the carotid circulation.

Ketamine – an NMDA receptor antagonist and works in a number of different ways in the brain.

 Pentoxifylline – a Xanthine derivative that belongs to a group of vasoactive drugs which improve peripheral blood flow. As with other xanthine derivatives, it relaxes certain smooth muscles including those of the peripheral vessels, thus causing vasodilation preventing spasm.

Dexamethasone – a potent synthetic steroid hormone which has anti-inflammatory and immunosuppressant properties.

Ketoprofen – an anti-inflammatory agent. This class of drugs have been used successfully in migraine treatment. They act to alleviate neurogenic inflammation and block prostanoid receptors to limit the inflammatory pain response.

Compounded Scar Cream

Our compounded scar creams, can meet each patient’s unique skin care and scar reducing needs. Compounded prescription scar creams will have the optimum dosage and frequency of administration to match a personalized plan, necessary for skin care. Our company provides a solution for various types of scars, where a “one size fits all approach,” such as over-the-counter medications or expensive laser treatments may not be suitable. Compounded scar creams are formulated with various effective ingredients in exact proportions. This custom approach can diminish scars resulting from surgeries, C-Sections, burns or injuries, and help restore the normal texture and color of your skin to the maximum extent possible.

Flucticasone Propinate USP Mircronized – a corticosteroid indicated for the relief of the inflammation and itchingssions of corticosteroid responsive dermatoses. Helps reduce swelling and redness

Levocetririzine Dihydrochloride – an antihistamine included for its anti-inflammatory properties

Pentoxifylline USP – a Xanthine derivative indicated for the treatment of intermittent claudication.

Gabapentin USP – a neuropathic medication included for its neural activity.

Prilocaine or Lidocaine – topical local anesthetics used for analgesic benefits.

Tranilast – an anti-inflammatory and anti-proliferative agent